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genotype-tissue expression database


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The Genotype-Tissue Expression (GTEx) project:基因组织 ...- genotype-tissue expression database ,2014-8-17 · The Genotype-Tissue Expression (GTEx) project:基因组织表.. OPEN580 volume 45 JuNe2013 naturegenetics commentary eventuallycompletely sequenced), genotypingdata linked genome-widegene expression patterns across widerange tis-sue types. Initially, resourcewould enable researchcommunity com-prehensive search eQTLs (both tissue-type speciic ...The Genotype-Tissue Expression (GTEx) projectHere we describe the Genotype-Tissue Expression (GTEx) project, which will establish a resource database and associated tissue bank for the scientific community to study the relationship between genetic variation and gene expression in human tissues.



The Genotype-Tissue Expression Project | Collections | AAAS

2020-9-11 · The Genotype-Tissue Expression Project. The panorama of human phenotypes arises from a mix of common and rare genetic variants, some of which affect how genes are expressed and spliced throughout the body. More than a decade ago, scientists aiming to better understand the effects of genetic diversity in healthy individuals launched the Genotype ...

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The GTEx Consortium atlas of genetic regulatory ... - bioRxiv

2019-10-3 · The Genotype-Tissue Expression (GTEx) project was established to characterize genetic effects on the transcriptome across human tissues, and to link these regulatory mechanisms to trait and disease associations. Here, we present analyses of the v8 data, based on 17,382 RNA-sequencing samples from 54 tissues of 948 post-mortem donors. We …

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Genotype-Tissue Expression Project (GTEx) - Pathology …

Launched by the National Institutes of Health (NIH) in September 2010, the Genotype-Tissue Expression (GTEx) Project created a resource that scientists can use to study how an individual’s genetic makeup affects tissue-specific gene expression. The end result was a database and a tissue bank that are available to researchers around the world. VAI’s Pathology and …

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公共数据库和大规模计划笔记4-GTEx数据库 - 云+社区 - 腾讯云

2019-2-15 · The Genotype–Tissue Expression (GTEx)计划目的是研究个人的基因组变异如何影响基因表达,导致生物学差异(人体组织和细胞的健康状态和患病状态)。 人体组织来自尸检、器官捐献和组织移植项目的多种不同组织类型(包括大脑、肝脏和肺部)近千个体的不同人体组织。

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Common Fund (CF) Genotype-Tissue Expression Project …

Nearly 90% of these GWAS-implicated sites lie outside of protein-coding sequences, suggesting that these variants might regulate gene expression. The goal of the Genotype-Tissue Expression (GTEx) project is to establish a resource database in which to study the relationship between genetic variation and gene expression in reference/non-diseased ...

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The Genotype-Tissue Expression project

2017-10-1 · The GTEx (Genotype-Tissue Expression) Consortium has established a reference catalogue and associated tissue biobank for gene-expression levels across individuals for diverse tissues of the human ...

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学徒作业-指定基因在指定组织里面的表达量热图 - 知乎

2020-3-31 · GTEx,The Genotype-Tissue Expression (GTEx) project,首次被提出来是2013年,上百位科学家联名在Nature Genetics杂志发表的文章首次介绍了“基因型-组织表达工程”,并成立了“基因型-组织表达研究联盟”(Genotype-Tissue Expression Consortium,GTEx

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The Genotype-Tissue Expression project

2017-10-1 · The GTEx (Genotype-Tissue Expression) Consortium has established a reference catalogue and associated tissue biobank for gene-expression levels across individuals for diverse tissues of the human ...

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Tissue expression of SV2A - Summary - The Human …

RNA EXPRESSION OVERVIEWi. RNA expression overview shows RNA-data from two different sources: Internally generated Human Protein Atlas ( HPA) RNA-seq data and RNA-seq data from the Genotype-Tissue Expression ( GTEx) project, as well as the consensus dataset which is based on a combination of both sources.

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Genotype Tissue Expression (GTEx) Project Body Map - BLAT

Genotype Tissue Expression (GTEx) Project Body Map. Credit: jwestdesign.

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Navigating the GTEx eQTL database and using TaqMan …

2018-11-9 · • Describe the importance of expression quantitative trait loci (eQTLs) • Demonstrate ways to use the Genotype-Tissue Expression (GTEx) database to fi nd eQTLs aff ecting the expression of various genes in various tissues • Illustrate how to fi nd Applied Biosystems™ TaqMan® Assays that can be used to verify and extend genome-

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公共数据库和大规模计划笔记4-GTEx数据库 - 云+社区 - 腾讯云

2019-2-15 · The Genotype–Tissue Expression (GTEx)计划目的是研究个人的基因组变异如何影响基因表达,导致生物学差异(人体组织和细胞的健康状态和患病状态)。 人体组织来自尸检、器官捐献和组织移植项目的多种不同组织类型(包括大脑、肝脏和肺部)近千个体的不同人体组织。

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Navigating the GTEx eQTL database and using TaqMan …

2018-11-9 · • Describe the importance of expression quantitative trait loci (eQTLs) • Demonstrate ways to use the Genotype-Tissue Expression (GTEx) database to fi nd eQTLs aff ecting the expression of various genes in various tissues • Illustrate how to fi nd Applied Biosystems™ TaqMan® Assays that can be used to verify and extend genome-

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(1) Genotype-Tissue Expression (GTEx) - Stanford …

2016-3-3 · (1) Genotype-Tissue Expression (GTEx) •Largest systematic study of genetic regulation in multiple tissues to date •53 tissues, 500+ donors, 9K samples, 180M gene RNA-Seq, 14M eQTL, 2M+ gene interactions, 30K+ gene annotations •Data •Donor •Age, Gender, Death Type •Tissue •RNA-Seq expression values •Gene •Tissue

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The Genotype-Tissue Expression (GTEx) project. | Broad ...

2013-6-3 · Here we describe the Genotype-Tissue Expression (GTEx) project, which will establish a resource database and associated tissue bank for the scientific community to study the relationship between genetic variation and gene expression in human tissues. Nat. Genet.

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GTEx简介 | eQTLGen | Blood eQTL - Life·Intelligence - 博客园

2020-9-23 · The Genotype-Tissue Expression (GTEx) project is an ongoing effort to build a comprehensive public resource to study tissue-specific gene expression and regulation. Samples were collected from 54 non-diseased tissue sites across nearly 1000 individuals, primarily for molecular assays including WGS, WES, and RNA-Seq. Remaining samples are available from …

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Genotype-Tissue Expression (GTEx) - NIH Common Fund

2021-7-1 · The Common Fund's Genotype-Tissue Expression (GTEx) Program established a data resource and tissue bank to study the relationship between genetic variants (inherited changes in DNA sequence) and gene expression (how genes are turned on and off) in multiple human tissues and across individuals.GTEx also increased our understanding of how gene …

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The GTEx Consortium atlas of genetic regulatory ... - bioRxiv

2019-10-3 · The Genotype-Tissue Expression (GTEx) project was established to characterize genetic effects on the transcriptome across human tissues, and to link these regulatory mechanisms to trait and disease associations. Here, we present analyses of the v8 data, based on 17,382 RNA-sequencing samples from 54 tissues of 948 post-mortem donors. We …

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TissGDB - UTH

2017-7-28 · TissGDB is the tissue-specific gene annotation database in cancer, aiming to provide a resource or reference for cancer and the related disease studies in the context of tissue specificity. We first collected 8,172 TissGenes across 22 tissue types, which are matched with the 28 cancer types of The Cancer Genome Atlas (TCGA) project, from three ...

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Developmental Genotype-Tissue Expression (dGTEx)

2022-3-10 · Developmental Genotype-Tissue Expression (dGTEx) The goal of the dGTEx initiative is to establish a resource database and associated tissue bank to study gene expression patterns in multiple reference tissues during human developmental stages, building upon the recently completed Genotype-Tissue Expression (GTEx) project.

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GTEx - Database Commons - CNCB

2019-7-30 · The Genotype-Tissue Expression (GTEx) project, sponsored by the NIH Common Fund, was established to study the correlation between human genetic variation and tissue-specific gene expression in non-diseased individuals. A significant challenge was the collection of high-quality biospecimens for extensive genomic analyses.

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Genotype-Tissue Expression (GTEx) | NCPI

2022-1-21 · The aim of the Genotype-Tissue Expression (GTEx) Project is to increase our understanding of how changes in our genes affect human health and disease with the ultimate goal of improving health care for future generations. GTEx will create a database that researchers can use to study how inherited changes in genes lead to common diseases.

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Genotype-Tissue Expression Project (GTEx) - Pathology …

Launched by the National Institutes of Health (NIH) in September 2010, the Genotype-Tissue Expression (GTEx) Project created a resource that scientists can use to study how an individual’s genetic makeup affects tissue-specific gene expression. The end result was a database and a tissue bank that are available to researchers around the world. VAI’s Pathology and …

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求帮助:NCBI官网站里如何知道基因在不同组织中的表达量 ...

2020-10-14 · The Genotype-Tissue Expression (GTEx) project is an ongoing effort to build a comprehensive public resource to study tissue-specific gene expression and regulation. Samples were collected from 54 non-diseased tissue sites across nearly 1000 individuals, primarily for molecular assays including WGS, WES, and RNA-Seq. Remaining samples are available from …

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